Cutaneous mucinosis in a patient taking ustekinumab for palmoplantar psoriasis

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Cutaneous mucinosis in a patient taking ustekinumab for palmoplantar psoriasis.

Discrete papular lichen myxedematosus (DPLM), asubset of localized lichen myxedematosus, is a rarecutaneous mucinosis of unknown etiology. We reporta case of a 57-year-old woman with palmoplantarpsoriasis who developed DPLM 8 weeks after addingustekinumab to a long-term course of methotrexate.The patient had previously failed 2 prior tumor necrosisfactor (TNF) inhibitors, adalimumab and etanerc...

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[Good response of hyperkeratotic palmoplantar psoriasis to ustekinumab].

Although only a small area of the body is affected in palmoplantar psoriasis or psoriasis of the palms and soles, this condition causes considerable functional impairment due to hyperkeratosis, fissures, and erythema, and occasionally inflammation and pustules. These symptoms may seriously interfere with the patient’s quality of life and may be disabling. Moreover, the lack of a standard treatm...

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Ustekinumab: differential use in psoriasis

Chronic plaque psoriasis is a systemic disease affecting over 3% of the population, and many patients are unsatisfied with their current treatment regimen. With advances in understanding of the pathophysiology of psoriasis, new therapeutic options are being developed. The newest of these agents, ustekinumab, offers patients rapid results and the convenience of four annual subcutaneous doses, wi...

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Cutaneous mucinosis of infancy

CMI: cutaneous mucinosis of infancy SHJCM: self-healing juvenile cutaneous mucinosis W e present a case of a 4-year-old fairskinned girl, with no significant medical history, who presented to the outpatient clinic of an academic medical center with an asymptomatic, flesh-colored, cobblestoned plaque on her lateral left thigh (Fig 1). Per the family’s report, the lesion had grown significantly s...

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Palmoplantar Psoriasis versus Eczema: Major Histopathologic Clues for Diagnosis

Background & Objectives:  Accurate differentiation of eczema and psoriasis can be difficult, especially in areas of palm and sole. This study was designed to evaluate histopathological features and identify statistically significant parameters in distinguishing palmoplantar psoriasis from eczema of these regions in patients referring to Razi Skin Hospital, Tehran, Iran. Methods: In a cross-sec...

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ژورنال

عنوان ژورنال: Dermatology Online Journal

سال: 2017

ISSN: 1087-2108

DOI: 10.5070/d3233034285